9h15-10h00 – Arrival and registration, coffee

10h00-10h15 – Greetings and opening session

Université Bourgogne Europe / UMR1231 CTM
Local organizers and ISNOC executive committee

10h15-11h30 – Lifetime achievement award

SESSION 1: Oxidative and inflammatory stess in tumor

11h30-11h55 – Moran Benhar – Mechanistic insights into reactive sulfur species mediated protection from
inflammatory cell death.

11h55-12h25 – Stéphanie Solier – Copper and plasticity.

12h30-13h55 – Lunch

13h55-14h20 – Christopher Switzer – Oxidative Signalling Mechanisms in Tumour Hypoxia.

14h20-14h45 – Maria Clara Franco – Title to be determined

14h45 – 14h55 – Presentation of the NO-CANCER-NET – Doctoral Network – Marie Sklodowska-Curie Actions
(MSCA) – Sharon Glynn (coordinator)

14h55-15h05 – Flash poster presentations – (1 slide – 120 sec)

SESSION 2: Control of thiol-based redox signaling

15h05-15h30 – Douglas D Thomas – Title to be determined 

15h30-15h55 – Katrina Miranda – Title to be determined 

15h55-16h20 – Denis Stuehr – Nitric oxide and hypoxia regulation of heme protein functions and potential role in cancer

16h20-16h50 – Coffee break

16h50-17h20 Young investigator session

17h20- 17h30 – Flash poster presentations

17h30 – 18h30 – Poster Session

SESSION 3 : NO production, metabolism and cell death

9h00-9h25 – Khosrow Kashfi – Challenging the Paradigm: Constitutive Expression of iNOS and the Case for
Revisiting NOS Nomenclature

9h25-9h50 – Erika Palmieri – Metabolic reprogramming of Tumor Microenvironment by Nitric Oxide

9h50-10h15 – Jordi Muntané – S-nitrosylation signature related to Sorafenib resistance in liver cancer cells

10h15-10h40 – Hugo Monteiro – Involvement of the NOS2/NOX4/GSNOR enzyme complex in the regulation of NOX4 activity in colorectal cancer cells

10h40-11h00 – Coffee break

11h00-11h10 – Flash poster presentations

SESSION 4: Angiogenesis, endothelial dysfunction

11h10-11h35 – Jean-Philippe Gratton – Regulation of normal and pathological angiogenesis by endothelial
nitric oxide synthase (eNOS).

11h35-12h05 – VB Schini-Kerth – Title to be determined

12h05-12h30 – Miriam Cortese – The role of NO/sGC pathway in erythropoiesis

12h40-14h00 – Lunch – poster session

14h00-14h30 – Young investigator session

SESSION 5: NO influence on the tumor-immune landscape: reprogramming the tumor microenvironment

14h30-14h55 – Daniel McVicar – Title to be determined

14h55-15h20 – Thomas Sauter – Computational drug sensitivity prediction

15h20-15h45 – speaker

15h45-16h15 – Coffee break

SESSION 6 : Therapeutic inhibition of iNOS / NO delivery – Part 1

16h15-17h05 – Jenny Chang – Title to be determined 

17h05-17h30 – speaker

17h30-17h55 – Khosrow Kashfi – Challenging the Paradigm: Constitutive Expression of iNOS and the Case for Revisiting NOS Nomenclature

17h55 – 18h30 – Poster Session

DINER 

SESSION 7 : Therapeutic inhibition of iNOS / NO delivery – Part 2

9h00-9h25 – Christian Serre – Biocompatible Metal-Organic Frameworks Gasotransmitters for Wound
Healing and Beyond.

9h25-9h50 – Isabelle Malfant – Nitric oxide Photorelease – Coordination Chemistry and Therapeutic Perspectives

9h50-10h15 – Greta Varchi – Targeting SMYD3-driven epigenetic pathways in cancer chemoresistance: advancing combination therapy strategies

10h15-10h45 Coffee break

10h45-11h05 – In-Kyu Park – Stimuli-Responsive Nanocarriers Enable Controlled Nitric Oxide Delivery to Reprogram Tumor Immunity and Amplify Therapeutic Impact

Awards

Round-table discussion: “NO, Tumor Microenvironment Regulation, and Tumor-Specific Targeting:
Challenges and Future Directions”

12h00 END OF MEETING