Members

We are a group of mouse neuroscientific researchers who work together to characterize gene function using an integrative approach from mouse genetics and systems biology to brain phenotyping, neuronal biology, animal behaviour and bioinformatics. We collaborate with clinicians locally and worldwide to enable direct comparisons between mice and patients with similar variants, providing unique insights into conserved neurodevelopmental processes.

 

We are recruiting !

Join us in Dijon if you are interested in genes, anatomy and behavior!

Technician Job

PhD Position

 

Members of the YALCIN Team in May 2024

 

Dr Binnaz YALCIN Research Director

Dr Binnaz YALCIN (CV_Binnaz_YALCIN_Longversion)

Email: Binnaz.Yalcin@inserm.fr Phone: +33 3 80 39 66 60

Dr Yalcin have contributed to important aspects of disease genetics using high-throughput genetic, genomic methodologies and mice as genetic models of cognitive disorders. Her ambition has always been to pursue her career in functional and translational disease genetics at the highest level. Dr Yalcin received her D.Phil in November 2007 from the University of Oxford under the supervision of Profs Flint and Mott. During her postdoctoral training (2007-2011), she became interested in outbred mice for genetic studies. She discovered the complexity of genomic structure in mice and how it relates to phenotypic variation. In 2011, she secured an EMBO Fellowship allowing her to move to Switzerland. For her own independent career, she obtained an Ambizione Fellowship in 2013 to work on the neurobiology of intellectual disability. She set up her own laboratory in 2016 at the IGBMC (Strasbourg, France) through an international call. One year later, the High Council for the Evaluation of Research and Higher Education scored her team as “excellent to outstanding with great future prospects”. She presented her work at 60 International Conferences of which 17 were under a formal invitation. She has received 17 awards/prizes, the most recent being the International Mary Lyon Award in recognition for an early-stage independent female researcher. To fund her research, she raised and managed a cumulative sum of 3.5 million EUR and employed six PhD students, three postdoctoral fellows, one engineer and seven research assistants (since 2016). She hosted in her laboratory more than 80 students worldwide at all levels (MSc, BSc, Intern, Assistants and ERASMUS). In 2019, she secured a tenured INSERM position (Assistant Professor equivalent) after being ranked Major in a national competition. In 2023, she was promoted to a tenured INSERM Research Director position (Associate Professor equivalent), with the distinction of “Remarkable Researcher”. She has 15 years of experience in mouse neurobiology and joined the Governance Board of the International Research Consortium for the Corpus Callosum and the International Mammalian Genome Society.

 

 

Dr Stephan COLLINS Senior Lecturer

Dr Stephan Christopher COLLINS (Full CV)

Email: Stephan.Collins@u-bourgogne.fr Phone: +33 3 80 39 66 68

Stephan holds a D.Phil from Oxford University in genetics of diabetes and completed a postdoctoral fellowship at the Wellcome Centre for Human Genetics working on metabolic syndrome and morbid obesity. After several years as an electrophysiologist in Prof Rorsman’s lab, he became interested in neurogenetics and joined Dr Yalcin’s team in 2016 to study mechanisms underlying comorbidities between cognition and obesity. Dr Collins has been a lecturer at the University of Burgundy-Franche-Comté since 2012. He provides a 196-hour service teaching in cell biology and animal biology for BSc students with additional teachings in genetics and neurosciences for MSc students. He has extensive experience in high-speed neuroanatomical data analysis, statistical analysis, project and database management and 3D imaging technology development.

 

 

Dr Siwar BEN AYACHE Postdoctoral Fellow

Siwar BEN AYACHE

Email: Siwar.Ben-Ayache@u-bourgogne.fr Phone: +33 3 80 39 66 11

Siwar holds a doctorate from the Higher Institute of Biotechnology of Monastir, University of Monastir, Tunisia. Her doctoral thesis focused on biological sciences and biotechnology. Currently, she holds a postdoctoral position in the H2020 project supported by the Partnership for Research and Innovation in the Mediterranean Region (PRIMA). Based on her academic background and her passion for neuroscience, she joined Dr. Yalcin’s team on October 1, 2023 to deepen her research in neurogenetics of mouse models and discover more in this field. Siwar has participated in the supervision of around fifteen master’s students and has good experience in data analysis, statistical analysis and animal experimentation.

 

 

Emilia SKUTUNOVA PhD student

Emilia SKUTUNOVA

Email: emilia.skutunova@inserm.fr Phone: +33 3 80 39 66 11

Emilia joined the Yalcin lab in July 2022, undertaking a two-month internship focused on 3D segmentation of the mouse brain. Rejoining the team in October 2023, she began her doctoral research, centered on deciphering the roles of CHD1L in the mammalian brain. Emilia holds a Bachelor’s degree in Cellular and Molecular Biology, as well as a Master’s degree in Cancer Biology from the University of Montpellier.

 

 

Charline PARISIS Research Assistant

Charline PARISIS

Email: Charline.Parisis@u-bourgogne.fr Phone: +33 3 80 39 66 11

I am Charline Parisis. Driven by a passion for research and a deep curiosity about understanding complex mechanisms, I joined the Yalcin lab in October 2023. This opportunity paves the way for my professionnal license but also broadens my horizon in the field of neuronal biology. With an Advanced Technician’s Certificate in Biotechnology earned in 2022, my expertise was further solidified through a 6-month position in 2023, where I worked on Pulmonary Pathologies, focusing on human lungs, in my role as a lab technician.

 

 

Beyza ZAYIM MSc student

Beyza ZAYIM

Email: beyzayim17@outlook.com Phone: +39 3475385228

I am Beyza Zayim, a dedicated biomedical engineer currently pursuing my master’s in the Erasmus Mundus Medical Imaging and Applications Program. This prestigious program is coordinated by the University of Girona, with esteemed partner institutions including the University of Bourgogne and the Università Degli Studi di Cassino e del Lazio Meridionale. My decision to specialize in this field stems from the rapidly growing use of Computer-Aided Diagnosis (CAD) in the medical sector. CAD systems have become invaluable tools, significantly improving the accuracy and efficiency of medical diagnoses. I am deeply motivated to advance research in Medical Image Analysis and CAD systems, with a particular focus on artificial intelligence, machine learning, pattern recognition, computer vision, and image processing. Currently, I am engaged in a two-month internship that centers on 3D segmentation of the mouse brain and fiducial markers’ detection. My goal is to leverage machine learning and deep learning techniques in conjunction with medical imaging to enhance diagnostic processes, ultimately contributing to improved human well-being.

 

 

Nikol NIKOLOVA BSc student

Nikol NIKOLOVA

Currently a bachelor student in University of Montpellier. Inspired by molecular genetics and extremely curious about the genetic causes of neurodevelopmental disorders. Joining the Yalcin’s team for an internship was an amazing opportunity to deepen my knowledge in neurogenetics, to learn new skills and to get motivated about pursuing a career in this field.

 

 

Aliénor VAUDENE BSc student

Aliénor VAUDENE

Email: Alienor_Vaudene@etu.u-bourgogne.fr Phone: +33 7 84 33 13 29

I am Aliénor Vaudene, and I discovered my passion for neuroscience during my ERASMUS experience in Ireland. This inspired me to continue my studies in this field. I completed my final year in cellular biology and physiology at the University of Dijon. I sought an internship at the NeuroGeMM laboratory to deepen my knowledge in neuroanatomy and neurogenetics, and I am very grateful for this opportunity. I will join the University of Bordeaux at the fall 2024, having been accepted into the prestigious Neurosciences Master’s program, EMN-Online.

 

 

Alumni members and their positions after leaving the lab

 

Visiting Professor

2016-2017                    Christel Depienne

Postdoctoral fellow

2017-2018                    Efil Bayam, IGBMC, Strasbourg, France (in collaboration with Dr J. Godin)

Graduated PhD students

2016-2021                    Charlotte Montillot, University of Bourgogne-Franche-Comté, France (01/09/2023)

2016-2021                    Perrine Kretz, University of Strasbourg, France (10/03/2021)

2013-2017                    Anna Mikhaleva, University of Lausanne, Switzerland (02/10/2017)

2012-2016                    Meghna Kannan, University of Strasbourg, France (23/11/2016)

 

Engineer

2021-2022                    Clémence Alibert, Inserm U1231 Dijon (currently PhD NeuroMyoGène)

Research Assistants

2022-2023                    Lucile Tonneau, University of Bourgogne-Franche-Comté, France

2020-2022                    Sylvie Nguyen, CHU Dijon, France (collaboration with Pr C. Thauvin)

2017-2018                    Emeline Aguilar, University of Strasbourg, France

2016-2019                    Marie-Christine Fischer, IGBMC, Strasbourg, France

2016-2018                    Christel Wagner, IGBMC, Strasbourg, France

2016-2017                    Léo Gagliardi, University of Strasbourg, France (Syngenta)

2015-2016                    Anais Duret

2015-2016                    Helen Whitley (Medical student)

2014-2016                    Rebecca Balz

MSc students (since 2016)

2024                             Hanzala Daud, University of Burgundy (collaboration with Pr A. Lalande)

2024                             Taiabur Rahman, University of Burgundy (collaboration with Pr A. Lalande)

2024                             Rania Farsi, University of Burgundy

2024                             Falilatou Saka, University of Burgundy

2023                             Juan Cisneros Jacome, University of Bourgogne-Franche-Comté, France (colla with Pr A. Lalande)

2022                             Emilia Skutunova, University of Montpellier (PhD)

2021                             Benazir Peerally, University of Sorbonne, France

2021                             Zineddine Allaoua, University of Bourgogne-Franche-Comté (Novolyze)

2021                             Adam Lahmar, University of Bourgogne-Franche-Comté, France (Arsene Innovation)

2021                             Axel Brocard, University of Bourgogne-Franche-Comté, France (Provepharm)

2020                             Maxence Milhau, University of Bourgogne-Franche-Comté (Leyton, Canada)

2020                             Bryan Capi, University of Bourgogne-Franche-Comté, France

2020                             Jules Roussey, University of Bourgogne-Franche-Comté, France

2019                            Charlotte Montillot, University of Nice Sophia Antipolis (postdoc)

2019                             Axel Da Costa Sousa, University of Bourgogne-Franche-Comté, France (CHU)

2018                             Marion Gaborit, University of Strasbourg (PhD INCI Strasbourg)

2017                             Mathilde Kobler (Medical student), University of Strasbourg, France

2017                             Maxime Meylan, University of Strasbourg (PhD 2022 Sorbonne University)

2017                             Sebastian Ciscares-Velazquez, University of Strasbourg, France (PhD Germany)

2017                             David Gualberto, University of Strasbourg, France (Merck)

2017                             Gilles Leininger, University of Strasbourg, France

2016                             Perrine Kretz, University of Strasbourg, France (PhD 2021)

2016                             Nestor Demeure, University of Strasbourg (PhD 2021 ENS Paris-Scalay, postdoc Berkeley Lab)

2016                             Jonathan Delevoye, University of Strasbourg, France

2016                             Laura Durieux, University of Strasbourg (PhD 2021 LNCA Strasbourg)

2016                             Somasekhar Jayaram (PhD Geneva)

BSc students (*Awarded the UNIL Summer Undergraduate Research Programme)

2024                            Chloé Ngon , University of Cergy Paris, France

2024                            Salma Zarfaoui , University of Paris-Est-Creteil, France

2023                            Ismail Salah, University of Bourgogne-Franche-Comté, France (Medicine)

2023                             Manon Lescutier, University of Bourgogne-Franche-Comté, France (MSc)

2022                             Rim Elmahjri, University of Bourgogne-Franche-Comté, France

2022                             Marion Bouiller, University of Bourgogne-Franche-Comté, France (DIXI medical)

2022                             Lola Tanneur, Magistère Européen de Génétique, Paris Diderot (MSc)

2021                             Juliette Delmas, University of Bourgogne-Franche-Comté, France

2021                             Juliette Henna, University of Bourgogne-Franche-Comté, France (MSc)

2021                             Salama Bou, University of Bourgogne-Franche-Comté, France

2021                             Flavie Theveny, University of Bourgogne-Franche-Comté, France (MSc)

2021                             Suzie Lebee, University of Bourgogne-Franche-Comté, France

2021                             Marie Thirion, University of Bourgogne-Franche-Comté, France (PhD Grenoble)

2021                             Marity Dessolain, University of Bourgogne-Franche-Comté, France (CNRS)

2020                             Gael Fleury, University of Bourgogne-Franche-Comté, France (EPFL)

2020                             Gaspard Boursier, University of Bourgogne-Franche-Comté, France (MSc)

2019                             Nawal Yahiaoui, University of Strasbourg, France (MSc Institut Pasteur, PhD ENS Paris)

2018                             Clara Bonnet, University of Poitiers, France (PhD Institut Curie)

2018                             Paula Hahn, University of Strasbourg (PhD Karolinska Institutet)

2018                             Maria Ossipenko, University of Strasbourg, France (MSc 2021, PhD Liège)

2017                             Sophie Lottiaux, University of Strasbourg, France (Clinical Manager Lyon)

2016                             Dylan Huynh, University of Strasbourg, France (MSc 2019, Octapharma)

2016                             Clara Casana Rico, University of Strasbourg, France (AbbVie Medical Affairs)

2016                             Elizabeth Ramos-Morales, University of Strasbourg, France (PhD 2021)

2015                             Luc Reymond (EPFL Lausanne)

2015                             Sarah Arthur* (PhD 2021 Canada)

2015                             Amicie De Pierrefeu (PhD 2018 CEA Paris, now at Ipsen)

Intern students

2024                             Nida Yardim, University of Clermont-Ferrand II, France

2024                             Eloise Domet, University of Burgundy, France

2024                             Maelle Tbatou, University of Burgundy, France

2023                             Océane Musset, University of Troyes, France (Magistère Européen de Génétique)

2023                             Emeline Richter, University of Troyes, France (Nurse School)

2023                             Elisa Mischler, University of Bourgogne-Franche-Comté, France (MSc)

2022                             Khadija Bayou, University of Bourgogne-Franche-Comté, France (MSc)

2021                             Maylis Joly, University of Bourgogne-Franche-Comté, France

2020                             Narjisse Kenani, University of Paris 18th, France

2019                             Elisia Isturiz, Supbiotech, Paris, France (Veracyte IO)

2019                             Nina Pigeonneau, University of Strasbourg, France

2017                             Emeline Aguilar, University of Strasbourg, France

2016                             Mariane Litt, University of Strasbourg, France (Transgene)

2016                             Saranya Ott, University of Strasbourg, France

2016                             Léo Gagliardi, University of Strasbourg, France (Syngenta)

2015                             Kevin Navarro (Manager Account, Lausanne)

Student Assistants

2015                             Mélina Gailly

2015                             Isabelle Herr

2015                             Amandine Delay

2015                             Livia Chrast (Medical student)

2015                             Lisa Haerri

Visiting International ERASMUS students (*Awarded the IGBMC Summer Research Internship Programme)    

2018                             Gulsah Evyapan, PhD student, Turkey

2018                             Emina Makedona*, BSc student, Greece

2017                             Ananya Pathak*, BSc student, India (Engineer New Delhi and Dublin)

2017                             Ezgi Mehmetoglu, BSc student, Turkey

2016                             Durna Kumruoglu, BSc student, Turkey

 

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